Investigating Tonsil-Derived Mesenchymal Stem Cells and Intestinal Stem Cells in Colitis Models
Current inflammatory bowel disease (IBD) treatments focus primarily on inflammation, with limited options for addressing intestinal fibrosis. A study assessed the effects of tonsil-derived mesenchymal stem cells (TMSCs) and TMSC-induced intestinal stem cell-like cells (T-ISCs) in two murine colitis models, including a DSS model commonly used to study ulcerative colitis, finding reductions in both fibrosis and inflammation.
