How Long Do IV-Administered MSCs Stay in the Body?

Intravenously administered mesenchymal stromal cells (MSCs) follow a predictable biodistribution, accumulating in the lungs before redistributing to the liver, spleen, and kidneys within the first week. While most MSCs are undetectable after a few weeks, some studies have found traces lasting up to 28 days, with variations based on age, disease state, and administration method.