Resetting Lupus: Off‑the‑Shelf CAR T Cell Therapy Offers a New Path to Remission
A first‑in‑kind, off‑the‑shelf CAR T cell therapy is giving new hope to people with severe, treatment‑resistant lupus by targeting and eliminating the autoreactive B cells that drive the disease. Early results from a UCI Health clinical trial show a dramatic reversal of long‑standing symptoms in one participant, hinting at the possibility of deep, lasting remission rather than temporary symptom control.