This comprehensive review explores emerging anti-aging strategies and their potential to maintain better health in old age. The study discusses several promising approaches, including:
- Autophagy enhancement: Stimulating cellular “housekeeping” to remove damaged components and maintain energy homeostasis.
- Senescent cell elimination: Removing cells that contribute to inflammation and tissue deterioration.
- Young blood plasma transfusion: Introducing factors from young blood to rejuvenate aging tissues.
- Intermittent fasting: Altering eating patterns to promote cellular repair and longevity.
- Adult neurogenesis enhancement: Boosting the production of new neurons in the aging brain.
- Physical exercise: Improving overall health and cognitive function through regular activity.
- Antioxidant intake: Combating oxidative stress with compounds like resveratrol and curcumin.
- Stem cell therapy: Using regenerative cells to repair and rejuvenate aging tissues.
The review highlights that while many of these strategies show promise in preclinical studies, further research is needed to determine their long-term efficacy and safety in humans. Some approaches, like intermittent fasting, physical exercise, and certain antioxidants, are considered ready for large-scale clinical trials due to their non-invasive nature and minimal side effects.The authors conclude that these emerging anti-aging strategies have the potential to become mainstream therapies for combating aging and postponing age-related diseases in the coming years, emphasizing the importance of continued research in this field.
