Exosome therapy has emerged as a prominent skincare trend in 2025, gaining attention for its potential to promote tissue regeneration and regulate the immune system. Exosomes are known for their ability to aid in wound healing, collagen production, reduced inflammation, and faster skin repair.
Dr. Madhuri Agarwal, MD and founder of Yavana Aesthetics, explains that exosomes are “tiny little messengers that communicate with adjacent or distant cells and carry and deliver regenerative biomolecules that help with tissue repair and cell regeneration.”
Dr. Jaishree Sharad, cosmetic dermatologist and founder of Skinfinitii Aesthetic Skin and Laser Clinic, adds that exosome therapy utilizes the therapeutic potential of exosomes to promote tissue regeneration and regulate the immune system.
Exosome therapy can be administered through in-clinic treatments or topical applications. In-clinic treatments, often paired with microneedling, platelet-rich plasma (PRP), or laser therapies, deliver faster and more noticeable results by reaching deeper layers of the skin. Dr. Agarwal emphasizes the importance of exosome stability for effectiveness, noting that in-clinic procedures involve creating microchannels in the skin to allow exosomes to work at a deeper level.
Topical exosome treatments offer convenience but are less concentrated and penetrate less deeply than in-clinic treatments. Dr. Sharad believes they can still be beneficial for hydrating the skin and providing surface-level rejuvenation. Both experts agree that exosome therapy is suitable for individuals in their late 20s to 30s, addressing skin concerns such as scarring, textured skin, enlarged pores, and fine lines.
